Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran

Authors

  • Davoud Mehrabani Gastroenterohepatology Research Center, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
  • Farhad Handijani Dermatology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
  • Mohammad Kazem Shahkarami Razi Vaccine and Serum Research Institute, Tehran, Iran
  • Nahal Hadi Departments of Bacteriology, Virology and
Abstract:

Background: Varicella–zoster virus (VZV) causes herpes zoster and varicella (Chicken-pox), usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in life. Objective: To determine the seroprevalence of VZV in elementary school children aged 6-10 years in Shiraz, Iran. Methods: A cross-sectional seroprevalence survey was conducted on 270 healthy subjects. All serum samples were investigated for immunoglobulin G (IgG) antibody against VZV using a commercial enzyme linked immunosorbent assay (ELISA). Results: Among the studied population, 175 (64.8%) had no detectable antibody levels. The overall seroprevalence rate was 35.2%. A breakdown of seropositivity to VZV according to age was as follows; 10 years old, 50%, 9 years old, 48.2%, 8 years old, 27.3%, 7 years old, 32.1%, and 6 years old, 13.2%. Conclusion: As VZV susceptibility in the studied age groups was higher than the expected rate, therefore childhood VZV vaccination is recommended in our region.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

seroprevalence of varicella-zoster virus in children from shiraz-iran

background: varicella–zoster virus (vzv) causes herpes zoster and varicella (chicken-pox), usually a mild disease which is diagnosed clinically with few complications. however, in neonates and healthy adults it can have a severe presentation. herpes zoster results from vzv reactivation later in life. objective: to determine the seroprevalence of vzv in elementary school children aged 6-10 years...

full text

Seroprevalence of Antibodies against Varicella Zoster Virus among Women before Marriage in Yazd, Iran

Background and Aims: Varicella-zoster virus (VZV) infection among pregnant women can cause a serious threat to the health of mother and fetus. Varicella is clearly less dangerous for immunized mothers. The aim of this study was to determine the prevalence of VZV antibody among women before marriage.  Materials and Methods: This cross-sectional study was conducted on 300 women of child-bea...

full text

Varicella-zoster virus seroprevalence in children and adolescents in the pre-varicella vaccine era, Germany

BACKGROUND In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the pre-varicella vaccine era in Germany, to identify factors associated with VZV seropositivity, and to assess the suitability of a commercially available ELISA for VZV seroepidemiologica...

full text

Seroprevalence of Varicella zoster virus antibody among young women before marriage in Sanandaj, Iran

BACKGROUND AND OBJECTIVES Varicella Zoster Virus (VZV) infection in pregnant women can cause complications for the mother and fetus. The aim of this study was to assess the immunity against VZV among young women before marriage. MATERIALS AND METHODS In this cross-sectional study 250 women attending health centers in Sanandaj, Iran, for pre-marital medical check-up were randomly selected. The...

full text

Seroprevalence of varicella-zoster virus among pregnant women in two teaching hospitals, Tehran, Iran

BACKGROUND AND OBJECTIVES Varicella zoster virus (VZV) can cause life-threatening disease in pregnant women. The aim of this study was to identify the VZV immune status in pregnant women and also determine the validity of self-reported history for chickenpox. METHODS Serologic testing for VZV was performed for 400 pregnant women attending prenatal care at clinics located in two teaching and r...

full text

Seroepidemiology of varicella zoster virus in healthcare workers in Babol, Northern Iran

Background: Varicella zoster virus (VZV) infection is one of the nosocomial infections and healthcare workers (HCWs) are at high risk group who work in the hospital with likelihood of varicella acquisition or transmission. This study evaluated the VZV seroprevalence in this high risk population in Babol, Iran. Methods: Serological testing for VZV using enzyme linked immunosorbent assay (ELISA)...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 3  issue 1

pages  43- 46

publication date 2006-03-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023